Articles
Oct 16, 2025

The Next Frontier in Oral Care: Moving Beyond Diagnostic AI to Therapeutic Solutions

The Next Frontier in Oral Care: Moving Beyond Diagnostic AI to Therapeutic Solutions

The dental AI revolution is well underway. Companies like Pearl and Overjet have raised hundreds of millions of dollars helping dentists diagnose cavities, bone loss, and other conditions more accurately. But here's the uncomfortable truth: after all that sophisticated AI analysis, patients still walk out of the dental office and go home to brush their teeth the same ineffective way, try to take care of their gums with different chemistry or instruments—yet we still have 50% of adults with gum disease and no meaningful change for decades.

This is the gap we're solving at ZERObrush.

The Problem: A Tale of Two Standards of Care

Here's the fundamental issue: the best dental care happens at the dental office. Professional cleanings, precise treatments, and advanced interventions deliver real results. But what happens at home today with oral care is very subpar. The results speak for themselves—despite countless variations in toothbrush designs, toothpaste chemistry, and gum care instruments, the outcomes remain stubbornly poor. Half of all adults still suffer from gum disease, a statistic that hasn't meaningfully improved in decades.

We want to change that.

The most advanced treatments—the ones that actually work—remain trapped behind the walls of dental offices. Meanwhile, consumers continue using generalized, one-size-fits-all tools that ignore their unique oral anatomy and specific health needs. We need the latest technology to finally provide real solutions. That's exactly what we're building.

The Breakthrough: Digital Twins Meets Additive Manufacturing

At ZERObrush, we've cracked what I believe is the hardest problem in personalized healthcare: how to capture individual anatomical data, use AI to design custom therapeutic solutions, and manufacture them at scale with exceptional economics.

Here's how our platform works:

Step 1: Digital Capture at Scale We capture comprehensive data from high-resolution digital impressions of your teeth and gums. This isn't just surface geometry—we're building a complete understanding of your oral anatomy and health needs.

Step 2: Automated AI Design to get a Digital Oral Twin: The digital twin is constructed using the latest in AI technology and model architecture, including our proprietary DentSam model. Our AI systems analyze impression data to build precise digital twins and automatically generate manufacturing-ready designs for personalized therapeutic devices with zero manual engineering time. What traditionally could take days per device now happens in seconds.

Step 3: Scalable Additive Manufacturing We're the first company in the world to manufacture fully personalized oral care devices using additive manufacturing at scale while maintaining exceptionally high gross margins. This breakthrough took years to develop and represents our competitive moat.

Starting with Superior Cleaning, Expanding to Everything

ZERObrush is starting by cleaning all of your teeth with greater efficacy than any manual or electric toothbrush could achieve. Our custom-fit device cleans your entire mouth in 30 seconds with precision tailored to your exact oral anatomy.

But this is just the START.

Using our digital twin infrastructure, we go beyond basic cleaning to tackle the full spectrum of oral care: gum care solutions, custom whitening treatments, personalized retainers, custom mouthguards, and novel precise therapy solutions that address your specific oral health challenges.

That is the vision of ZERObrush—a comprehensive platform that finally brings professional-grade, personalized oral care into the home through the latest technology.

The Platform Economics Revolution

Here's what makes this different from traditional personalized medical devices: we've eliminated the customization cost barrier through full automation. Traditional personalized devices fail economically because each customization requires expensive human engineering time. Our automated design system removes this bottleneck entirely, delivering:

  • Near-zero marginal design costs per unit
  • High gross margins through optimized additive manufacturing at scale
  • Attractive contribution margins that improve as we scale volume

Each digital twin becomes a recurring revenue engine across multiple therapeutic products, all manufactured with superior unit economics.

Why This Matters Now

The dental AI diagnostic market has validated that artificial intelligence can transform oral healthcare. Pearl, Overjet, and others have proven there's massive value in applying AI to dental data.

We're building the logical next step: moving from diagnosis to treatment. From identifying problems to solving them at home with the latest technology.

The oral care market is $50 billion globally, and after decades of stagnation, it's ready for disruption. Consumers are increasingly sophisticated about healthcare and demanding better solutions. The technology stack we need—AI, digital manufacturing, advanced materials—has finally matured to make this vision economically viable.

The Bigger Picture

ZERObrush represents something larger than oral care. We're proving that the combination of digital twin technology, AI-driven automated design, and scalable additive manufacturing can professionalize at-home healthcare across categories.

Think about it: if we can deliver professional-grade, personalized oral care at home with viable unit economics, what other areas of healthcare could benefit from this approach?

The future of healthcare isn't just about better diagnosis—it's about bringing effective, personalized treatment home through intelligent platforms that understand your unique anatomy and needs.

The question isn't whether this future will arrive. The question is who will build it first.